Cilostazol .
Price 100 INR/ Kilograms
Cilostazol . Specification
- Loss on Drying
- Not more than 0.5%
- Storage
- Store in a cool, dry place, protected from light.
- Melting Point
- 159-161C
- Boiling point
- Not available (decomposes before boiling)
- Structural Formula
- Refer to image or chemical structure registry.
- Molecular Formula
- C20H27N5O2
- Smell
- Odorless
- Heavy Metal (%)
- Not more than 20 ppm
- EINECS No
- 680-186-2
- HS Code
- 29349900
- Solubility
- Practically insoluble in water; freely soluble in acetone, acetonitrile, methanol.
- Particle Size
- Typically 90% < 10 microns
- Shelf Life
- 24 months
- Molecular Weight
- 369.46 g/mol
- Poisonous
- No (when used at therapeutic doses)
- Color
- White to off-white
- Medicine Name
- Cilostazol
- Chemical Name
- 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
- CAS No
- 73963-72-1
- Type
- Other
- Grade
- Other
- Usage
- Used as an antiplatelet agent to reduce symptoms of intermittent claudication.
- Purity(%)
- >= 99%
- Appearance
- White to off-white crystalline powder
- Physical Form
- Solid
- Microbial Limits
- Total microbial count NMT 1000 CFU/g
- Stability
- Stable under recommended storage conditions
- Optical Rotation
- Not applicable (not chiral)
- Residual Solvents
- Complies with ICH guidelines
- Density
- Approx. 1.33 g/cm3
- Related Substances
- Not more than 0.5%
- Identification
- IR and HPLC conform to standard
Cilostazol . Trade Information
- Minimum Order Quantity
- 1 Kilograms
- Supply Ability
- 2000 Kilograms Per Day
- Delivery Time
- 1 Days
- Main Domestic Market
- All India
About Cilostazol .
Cilostazol is a medication that helps to open the blood vessels to improve the circulation by keeping platelets from sticking together. It helps in reducing aching, crampy, tired and pain in legs that occurs during walking and goes away with rest due to poor circulation in arteries of the legs. Cilostazol belongs to platelets aggregation inhibitors with an ability to decrease clots forming property of platelets. It has a chemical formula C20H27N5O2 with a water solubility of 1.678 milligram per liter at 25 degree Celsius. Do not take this drug if you are allergic to it and consult your doctor first before consumption. Some of the side effects that may occur due to overdose are severe headache, fast & irregular heartbeat, severe dizziness etc.,
Stringent Quality Control Ensures Purity and Safety
Cilostazol undergoes comprehensive quality assessment, including HPLC and IR identification, with related substances maintained below 0.5%. Residual solvents adhere to ICH limits, and the total microbial count does not exceed 1000 CFU/g, ensuring pharmaceutical-grade purity and safety for end-use.
Optimal Physical and Chemical Properties
With a molecular weight of 369.46 g/mol and a density of approximately 1.33 g/cm, Cilostazol demonstrates ideal physical characteristics for formulation. Its white to off-white appearance, fine particle size, and excellent solubility in organic solvents make it versatile for various pharmaceutical applications.
Reliable Storage and Longevity
Cilostazol remains stable for up to 24 months when stored in a cool, dry environment protected from light. Its shelf life and odorless, non-poisonous nature at therapeutic doses further enhance its practicality and safety for manufacturers and end-users.
FAQs of Cilostazol .:
Q: What are the recognized quality standards for Cilostazol, and how are these verified?
A: Cilostazol meets identification standards through IR and HPLC analysis, while complying with ICH regulations for residual solvents. Additional tests ensure related substances are below 0.5% and heavy metals do not exceed 20 ppm. Each batch is thoroughly analyzed for purity, safety, and efficacy.Q: How should Cilostazol be stored to maintain its stability and effectiveness?
A: To preserve stability and maximize shelf life (24 months), Cilostazol should be stored in a cool, dry place, shielded from light. Recommended storage conditions help prevent degradation and maintain its potency for pharmaceutical processing or distribution.Q: What are the main uses and benefits of Cilostazol?
A: Cilostazol is primarily used as an antiplatelet agent to reduce symptoms of intermittent claudication, improving blood flow in individuals with peripheral vascular disease. Its efficacy and safety at therapeutic doses make it a valuable option for patients requiring enhanced circulation.Q: Where can Cilostazol be sourced from, and who supplies it?
A: Manufacturers, distributors, exporters, importers, suppliers, and traders in India provide pharmaceutical-grade Cilostazol. The product is available for both domestic and international markets, backed by regulatory compliance and reliable quality assurance.Q: What is the recommended process for handling and formulating Cilostazol in a manufacturing environment?
A: Cilostazol is typically supplied as a white to off-white crystalline powder with particle sizes (90% < 10 microns) optimized for formulation. It is insoluble in water but freely dissolves in solvents like acetone, acetonitrile, and methanol, facilitating ease of blending and incorporation into dosage forms.Q: Does Cilostazol pose any toxicity risks, and what is its safety profile?
A: Cilostazol is not considered poisonous when used within therapeutic ranges. It is odorless and displays a robust safety profile when handled as per recommended guidelines, with regular testing to ensure absence of harmful levels of residual solvents, heavy metals, or microbial contamination.
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