Acenocoumarol
Price 100 INR/ Kilograms
Acenocoumarol Specification
- Melting Point
- 184-186C
- Smell
- Odorless
- Shelf Life
- 24 months (when properly stored)
- Loss on Drying
- 0.5%
- Taste
- Characteristic
- Color
- White to off-white
- Solubility
- Slightly soluble in water, soluble in organic solvents (ethanol, methanol, acetone)
- Boiling point
- Not applicable (decomposes before boiling)
- EINECS No
- 205-816-9
- Molecular Weight
- 353.33 g/mol
- Poisonous
- Yes (anticoagulant, handle with care)
- HS Code
- 29322090
- Structural Formula
- See image reference or chemical structure
- Heavy Metal (%)
- 0.001%
- Storage
- Store in a cool, dry place, tightly closed container, light and moisture sensitive
- Ph Level
- Not applicable (solid compound)
- Molecular Formula
- C19H15NO6
- Particle Size
- Micronized, typically <100 microns
- Medicine Name
- Acenocoumarol
- Chemical Name
- 4-Hydroxy-3-[(1-(4-nitrophenyl)-3-oxobutyl)]-2H-chromen-2-one
- CAS No
- 152-72-7
- Type
- Other
- Grade
- Other
- Usage
- Anticoagulant, pharmaceutical intermediate
- Purity(%)
- 99% (typical)
- Appearance
- White to off-white crystalline powder
- Physical Form
- Solid
- Stability
- Stable under recommended conditions
- Bioavailability
- High (on oral administration)
- Therapeutic Category
- Oral anticoagulant, vitamin K antagonist
- Packaging
- Sealed containers, nitrogen filled if required
- Storage Temperature
- 2-8C recommended
- pKa Value
- 5.2
- Identification Method
- HPLC, IR, NMR, MS
- Residual Solvents
- Complies with ICH Q3C guidelines
- Assay (HPLC)
- 99.0%
- Related Substances
- 0.1% (individual impurity)
Acenocoumarol Trade Information
- Minimum Order Quantity
- 1 Kilograms
- Supply Ability
- 2000 Kilograms Per Day
- Delivery Time
- 1 Days
About Acenocoumarol
Acenocoumarol is a pharmaceutical compound which is used as blood thinner that prevent blood coagulation. Its molecular formula is C19H15NO6 with a molecular weight of 353.3 gram per mol. It is an anticoagulant agent is commonly used to treat blood clots and to prevent stroke in people that are suffering from valvular heart disease or have artificial heart valves. This drug can be used to manufacture medicines in different forms such as pill, tablets or in medical equipments such as heart-lung and dialysis machines. Acenocoumarol prevents the reduction of vitamin K, which results in the reduction of the thrombogenicity of clots. Patients on this drug are not allowed to donate blood.
Superior Quality Control
Acenocoumarol is produced with strict identification methods such as HPLC, IR, NMR, and MS, guaranteeing compound authenticity and purity. Each batch undergoes rigorous testing to meet 99% purity and less than 0.1% impurities, ensuring patient safety and product consistency.
Optimal Formulation and Packaging
The compounds micronized particle size (typically less than 100 microns) increases its oral bioavailability, and its stable crystalline form protects its potency. Packaging in sealed, nitrogen-filled containers prevents moisture and oxidative damage, preserving its quality during transport and storage.
Reliable Pharmaceutical Applications
Acenocoumarol serves as a crucial agent in the prevention of blood clots and is widely used in pharmaceutical formulations as an anticoagulant. Its well-characterized pharmacokinetic properties and stability make it a suitable choice for various clinical and research applications.
FAQs of Acenocoumarol:
Q: How is Acenocoumarol identified and characterized during quality control?
A: Acenocoumarol is identified through advanced analytical techniques including High-Performance Liquid Chromatography (HPLC), Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS), ensuring precise confirmation of its chemical structure and purity.Q: What are the recommended storage conditions for Acenocoumarol?
A: It is best to store Acenocoumarol in a tightly sealed container, away from light and moisture, at a temperature between 28C. This help maintains its stability and extends its shelf life to up to 24 months.Q: When should Acenocoumarol be considered for pharmaceutical use?
A: Acenocoumarol is indicated for oral administration in the prevention and treatment of thromboembolic disorders, making it suitable whenever a vitamin K antagonist anticoagulant is clinically required.Q: Where does Acenocoumarol find common applications?
A: Acenocoumarol is predominantly used in the pharmaceutical industry as an anticoagulant in the management of blood clot-related conditions, and may also serve as an intermediate in the synthesis of other pharmaceuticals.Q: What benefits does micronized Acenocoumarol offer over non-micronized forms?
A: Micronized Acenocoumarol, with a particle size typically under 100 microns, allows for enhanced absorption and higher bioavailability when administered orally, potentially improving therapeutic outcomes.Q: How does Acenocoumarol comply with safety and impurity standards?
A: The product adheres to ICH Q3C guidelines for residual solvents and maintains individual related substances at or below 0.1%, with heavy metal content under 0.001%, ensuring high safety and quality levels for pharmaceutical applications.
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