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Amphotericin B
Amphotericin B

Amphotericin B

Price 100 INR/ Kilograms

MOQ : 1 Kilograms

Amphotericin B Specification

  • Molecular Weight
  • 924.08 g/mol
  • Molecular Formula
  • C47H73NO17
  • Solubility
  • Slightly soluble in water; soluble in DMSO, DMF and methanol
  • Poisonous
  • Yes (toxic)
  • Boiling point
  • Not applicable (decomposes before boiling)
  • Color
  • Yellow to orange
  • Taste
  • Bitter
  • Ph Level
  • 5.0 - 7.0 (in solution)
  • Shelf Life
  • 24 months
  • Heavy Metal (%)
  • 0.001%
  • Storage
  • Store at 2-8C, protect from light and moisture
  • EINECS No
  • 215-742-2
  • Structural Formula
  • See image reference or supplied documentation
  • Smell
  • Odorless
  • Loss on Drying
  • 8%
  • HS Code
  • 29419090
  • Particle Size
  • Not more than 40 microns
  • Melting Point
  • 170C (decomposes)
  • Medicine Name
  • Amphotericin B
  • Chemical Name
  • Amphotericin B
  • CAS No
  • 1397-89-3
  • Type
  • Other
  • Grade
  • Other
  • Usage
  • Antifungal; treatment of systemic fungal infections
  • Purity(%)
  • 98%
  • Appearance
  • Yellow to orange crystalline powder
  • Physical Form
  • Solid
  • Residual Solvents
  • As per ICH guidelines
  • Packing
  • Packaged in sterile, light-resistant containers
  • Microbial Limit
  • < 1000 CFU/g
  • Optical Rotation
  • +30 to +45 (c=1, DMF)
  • Endotoxin Level
  • < 0.5 EU/mg
  • Assay Method
  • HPLC
  • Water Content
  • < 8%
  • Identification
  • IR spectrum conforms to standard
 

Amphotericin B Trade Information

  • Minimum Order Quantity
  • 1 Kilograms
  • Supply Ability
  • 2000 Kilograms Per Day
  • Delivery Time
  • 1 Days
 

About Amphotericin B

Amphotericin B is an anti-fungal or anti-protozoal drug which is used in the medication of various fatal fungal infections. Some of the infections such as aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis can be treated using this drug. It is not suitable for minor fungus problems like yeast infection of the mouth and esophagus. Amphotericin B can only be taken as per the doctors prescription as it may lead to several. It is an irritant compound may cause skin, eye and respiratory irritation on single exposure. The drug binds to sterols in the cell membrane of susceptible fungi that allows leakage of intracellular components which ultimately result in death of fungi cell.

Amphotericin B

  • USDMF
  • CEP/COS
  • DCGI



Comprehensive Antifungal Activity

Amphotericin B is renowned for its effectiveness in treating severe, systemic fungal infections. Its broad-spectrum efficacy makes it an essential medicine in hospitals and healthcare facilities. This compound acts by binding to fungal cell membranes, thereby disrupting their structural integrity and leading to the elimination of pathogenic fungi. As a result, it offers significant benefits for individuals with compromised immune systems.


Strict Quality and Safety Standards

Our Amphotericin B is rigorously evaluated per ICH guidelines for residual solvents and tested for heavy metals, microbial limits, and endotoxin levels. Each batch undergoes HPLC assay and IR spectrum verification, ensuring superior quality, safety, and consistency. Packaged in sterile, light-resistant containers, the product is maintained at the highest standards.


User-Centric Packaging and Storage

To maximize potency and stability, Amphotericin B is packaged under sterile conditions in containers that shield it from light exposure. The product must be stored at 2-8C and protected from both light and moisture. These measures help maintain a shelf life of up to 24 months, ensuring its effectiveness whenever it is needed.

FAQ's of Amphotericin B:


Q: How should Amphotericin B be stored for optimal stability?

A: Amphotericin B must be kept refrigerated at temperatures between 2C and 8C, in its original sterile, light-resistant container. Protect it from both light and moisture to preserve its potency and to maintain its 24-month shelf life.

Q: What is the primary usage of Amphotericin B?

A: Amphotericin B is an antifungal medication, primarily used to treat systemic fungal infections. It is suitable for patients with severe or invasive fungal diseases, particularly in immunocompromised individuals.

Q: When does Amphotericin B decompose, and what is its melting point?

A: Amphotericin B has a melting point of approximately 170C, at which it decomposes. Boiling is not applicable because the compound breaks down before reaching its boiling point.

Q: Where can you source Amphotericin B in India?

A: Amphotericin B is available through multiple channels in India, including manufacturers, exporters, suppliers, distributors, and traders. Ensure you source it from certified and compliant vendors for the best quality.

Q: What benefits are associated with using Amphotericin B that has low endotoxin and microbial content?

A: With an endotoxin level below 0.5 EU/mg and a microbial load under 1000 CFU/g, this Amphotericin B formulation offers enhanced safety, reducing the risk of pyrogenic and microbial contamination during clinical use.

Q: How is the purity and quality of Amphotericin B verified?

A: Each batch is analyzed using High-Performance Liquid Chromatography (HPLC) for assay, while identification is confirmed by IR spectrum. Further tests ensure compliance with residual solvents, water content, and heavy metal limits.

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