Sevelamer Carbonate
Price 100 INR/ Kilograms
Sevelamer Carbonate Specification
- Smell
- Odorless
- Molecular Formula
- (C4H11N)n.(C3H7N)m.CO3
- Heavy Metal (%)
- <0.002%
- Poisonous
- Non-poisonous
- HS Code
- 29221990
- Color
- White to off-white
- Ph Level
- 7.0 to 8.0 (1% suspension in water)
- Melting Point
- Decomposes before melting
- Molecular Weight
- Varying (polymeric compound)
- Storage
- Store in a cool, dry, tightly closed container
- Solubility
- Insoluble in water; swells in aqueous solutions
- Taste
- Tasteless
- Particle Size
- Usually <250 microns
- Structural Formula
- [C4H11N]n[C3H7N]mCO3
- Shelf Life
- 2 years when properly stored
- Loss on Drying
- <6%
- EINECS No
- None assigned
- Medicine Name
- Sevelamer Carbonate
- Chemical Name
- Poly(allylamine-co-N,N-diallyl-1,3-diaminopropane) carbonate
- CAS No
- 845273-93-0
- Type
- Other
- Grade
- Other
- Usage
- Pharmaceutical intermediate, used to control hyperphosphatemia in patients with chronic kidney disease
- Purity(%)
- >99%
- Appearance
- White to off-white, crystalline powder
- Physical Form
- Solid
- Moisture Content
- Not more than 6.0%
- Residual Monomer
- <0.2%
- Storage Temperature
- Below 25C
- pKa
- Less than 9.0
- Packaging
- Available in HDPE drums, double polyethylene bags
- Stability
- Stable under recommended storage conditions
Sevelamer Carbonate Trade Information
- Minimum Order Quantity
- 1 Kilograms
- Supply Ability
- 2000 Kilograms Per Day
- Delivery Time
- 1 Days
About Sevelamer Carbonate
Sevelamer Carbonate is a pharmaceutical compound that is also known as phosphate binging drug. It is used to lower the level of phosphate in the patients that are suffering from kidney diseases. This drugs helps to maintain the the body health by decreasing blood phosphate levels to make your bones strong or prevent unsafe production of minerals in human body which further reduces the risk of heart diseases and strokes. Sevelamer Carbonate may lead to side effects such as choking, trouble swallowing, constipation, stomach pain, tiredness, itching and joint pain in case of overdose and interaction with other medicines. It is also advised to consult your doctor if you recently had stomach or intestinal surgery before taking this drug.
Other Details
| Packaging Size | 1kg |
| Product Type | API |
Applications in Pharmaceutical Industry
Sevelamer Carbonate serves as a crucial pharmaceutical intermediate, primarily used to manage elevated phosphate levels in patients with chronic kidney disease. Its high purity and stability under proper storage make it ideal for pharmaceutical formulations. With its inability to dissolve in water, this compound efficiently limits phosphate absorption in the digestive tract, benefiting patients who require careful management of mineral balance.
Storage and Packaging Standards
Sevelamer Carbonate is packaged in tightly sealed HDPE drums, lined with double polyethylene bags to protect against moisture. To ensure optimal stability and effectiveness, the product should be stored below 25C in a cool, dry place. When kept under recommended conditions, its shelf life extends up to two years, maintaining low moisture content and preventing contamination.
FAQs of Sevelamer Carbonate:
Q: How should Sevelamer Carbonate be stored for maximum stability?
A: Sevelamer Carbonate should be stored below 25C in a tightly closed container, away from moisture and direct sunlight. Proper storage in a cool, dry place using HDPE drums with double polyethylene bags preserves its stability and extends shelf life up to two years.Q: What is the main usage of Sevelamer Carbonate in the pharmaceutical sector?
A: Sevelamer Carbonate is primarily employed as an oral phosphate binder to control hyperphosphatemia in patients with chronic kidney disease. Its unique structure allows it to bind phosphate in the digestive tract, reducing absorption and aiding in mineral balance.Q: When does Sevelamer Carbonate degrade, and what precautions should be taken?
A: Sevelamer Carbonate decomposes before it melts and remains stable under temperatures below 25C. It is important to avoid storing this compound at elevated temperatures or in humid conditions to prevent degradation and ensure consistent quality.Q: Where can Sevelamer Carbonate be sourced in India?
A: Sevelamer Carbonate is available across India through authorized distributors, exporters, importers, manufacturers, suppliers, and traders specializing in pharmaceutical intermediates. Reliable sourcing ensures product quality and compliance with industry standards.Q: What process is involved in ensuring the quality of Sevelamer Carbonate?
A: Quality is ensured through stringent tests, including verification of purity (>99%), residual monomer content (<0.2%), loss on drying (<6%), particle size, and heavy metal content (<0.002%). Packaging in moisture-resistant containers further maintains product integrity.Q: How does Sevelamer Carbonate benefit patients with chronic kidney disease?
A: By binding to dietary phosphate in the gastrointestinal tract, Sevelamer Carbonate prevents its absorption into the bloodstream, which helps control phosphorus levels. This reduces risks associated with high phosphate, such as bone and cardiovascular problems, enhancing patient outcomes.
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