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Alfacalcidol
Alfacalcidol Specification
- Melting Point
- 136-141C
- Solubility
- Practically insoluble in water, freely soluble in ethanol, chloroform, and ether
- Color
- White
- Molecular Weight
- 400.64 g/mol
- EINECS No
- 255-416-0
- Loss on Drying
- 1.0%
- Molecular Formula
- C27H44O2
- Structural Formula
- C27H44O2
- Heavy Metal (%)
- 0.002%
- Smell
- Odorless
- Shelf Life
- 2 years
- Boiling point
- Not available (decomposes)
- Poisonous
- Non-poisonous in specified pharmaceutical dose
- Storage
- Store in a cool, dry place, protected from light
- HS Code
- 29362900
- Taste
- Tasteless
- Medicine Name
- Alfacalcidol
- Chemical Name
- (5Z,7E,22E)-(1R,3R,5Z,7E,22E,24S)-9,10-secocholesta-5,7,10(19),22-tetraene-1,3,24-triol
- CAS No
- 41294-56-8
- Type
- Other
- Grade
- Other
- Usage
- Pharmaceutical raw material, used for treatment of osteoporosis and renal osteodystrophy
- Purity(%)
- 99.0%
- Appearance
- White to off-white crystalline powder
- Physical Form
- Solid
- Stability
- Stable under recommended storage conditions
- Microbial Limits
- Complies with pharmacopeial standards
- Regulatory Compliance
- USP/BP/EP
- Optical Rotation
- +103 to +107
- Identification
- Complies with reference standard (IR, MS, HPLC)
- Packaging Size
- 1g, 5g, 10g, 100g (customized packaging available)
- Therapeutic Area
- Bone metabolism, vitamin D deficiency
- Residual Solvents
- Within ICH limits
- Related Substances
- 1.0%
- Packaging Type
- Amber glass bottle or aluminum foil bag
- Applications
- Active Pharmaceutical Ingredient (API) for vitamin D analog therapy
- Assay
- 99.0% to 102.0% (HPLC)
Alfacalcidol Trade Information
- Minimum Order Quantity
- 1 Kilograms
- Supply Ability
- 2000 Kilograms Per Day
- Delivery Time
- 1 Days
About Alfacalcidol
Alfacalcidol
Alfacalcidol is a source of vitamin D which is used as a supplement for human to improve bone health. It is mainly used to treat osteoporosis by stimulating the intestinal calcium absorption, increases urinary excretion and suppresses parathyroid hormone secretion. It is mainly used for old people for increasing the bone strength. Alfacalcidol can also be used as a poultry feed additive to enhance the quality of the food items. This composition is very important for regulating the calcium balance and bone metabolism. It is mild toxic in its nature and its overdose may result in side effects like vomiting, weakness, headache, dry mouth, constipation and muscle pain.
- Synonym : 1-alpha-Hydroxycholecalciferol; (1alpha,3beta,5Z,7E)-Secocholesta-5,7,10(19)-triene-1,3-diol
- Molecular Formula : C27H44O2
- Molecular Weight : 400.64
- Specifications : AVAILABLE ON REQUEST
- Packing : EXPORT WORTHY PACKING
- Availability : FOR R&D PURPOSE ONLY
Superior Quality & Compliance
Alfacalcidol ensures pharmaceutical-grade quality verified by HPLC, IR, and MS, with an assay ranging from 99.0% to 102.0%. Complying with stringent USP, BP, and EP pharmacopeial standards, each batch undergoes rigorous identification and impurity checks. The product is non-poisonous at prescribed doses and meets all residual solvent and microbial limits as per ICH guidelines, providing reliability and safety for formulators and researchers.
Wide Application in Bone Health
Designed as a vitamin D analog, Alfacalcidol is pivotal in addressing bone metabolism disorders, such as vitamin D deficiency, osteoporosis, and renal osteodystrophy. Its role as an API makes it suitable for various pharmaceutical formulations aimed at improving calcium absorption and bone mineralization. Its efficacy and purity are trusted in both clinical and research settings.
Custom Packaging & Global Distribution
Available in 1g, 5g, 10g, and 100g packagingplus custom sizesAlfacalcidol is securely packed in amber glass bottles or aluminum foil bags to preserve integrity. Manufacturers, suppliers, and distributors in India ensure worldwide export and import, catering to specific requirements of pharmaceutical businesses and research labs.
FAQs of Alfacalcidol:
Q: How should Alfacalcidol be stored for optimal stability?
A: Alfacalcidol should be stored in a cool, dry place, protected from light, to maintain its stability and efficacy throughout its two-year shelf life. Avoid exposure to moisture and direct sunlight.Q: What is the primary use of Alfacalcidol in pharmaceuticals?
A: Alfacalcidol is mainly employed as an active pharmaceutical ingredient for the treatment of bone metabolism disorders, including osteoporosis, renal osteodystrophy, and vitamin D deficiency. It enhances calcium absorption and promotes bone health.Q: When is Alfacalcidol recommended in therapy?
A: Alfacalcidol is recommended when there is a clinical need to manage conditions arising from abnormal bone metabolism or low vitamin D, such as in patients with chronic kidney disease or those at risk of osteoporosis.Q: Where can Alfacalcidol be sourced and in what packaging options?
A: Alfacalcidol can be obtained from reputable distributors, manufacturers, and exporters in India. Packaging is available in 1g, 5g, 10g, 100g, and customized sizes, using amber glass bottles or aluminum foil bags for preservation.Q: What regulatory standards does Alfacalcidol comply with?
A: This product adheres to USP, BP, and EP guidelines, ensuring it meets global pharmacopeial requirements. It is subject to strict quality control for assay, impurities, residual solvents, and microbial content.Q: How is Alfacalcidol typically processed for use in formulations?
A: Due to its practical insolubility in water but good solubility in ethanol, chloroform, and ether, Alfacalcidol is generally processed via solvent-based methods during the manufacturing of tablet or capsule formulations.Q: What benefits does Alfacalcidol offer healthcare providers and patients?
A: Alfacalcidol delivers well-characterized potency, high purity, and robust therapeutic results in vitamin D analog therapy, facilitating improved bone strength and health while minimizing impurities and ensuring dosage consistency.Price 100 INR/ Kilograms
- Minimum Order Quantity
- 1 Kilograms
- Supply Ability
- 2000 Kilograms Per Day
- Delivery Time
- 1 Days
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GST : 24AKEPV9396A1ZU
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