Olopatadine Hydrochloride

About Olopatadine Hydrochloride

Olopatadine Hydrochloride is a pharmaceutical compound that can be used to cure various allergies like itching, watery-eyes and redness in eyes. It reduces histamine that is a natural chemical produced in body. Its chemical formula is C21H24ClNO3 with a molecular weight of 373.9 grams per mol. It prevents the binding of histamine with H1 receptor to reduce the effect of the biologically active substance on capillaries, smooth bronchial muscle and gastrointestinal. Olopatadine Hydrochloride may show some temporary side effects sch as headache, sore throat, eye discomfort, change in taste therefore it is highly recommended to consult doctor before consumption.

Olopatadine Hydrochloride

Key Features and Physical Properties

Olopatadine Hydrochloride is recognized for its high purity, excellent solubility in water and methanol, and stable solid form. Typically offered as a micronized powder with particle size D90 < 20 m, it remains practically odorless and possesses a specific optical rotation of +110 to +120. It decomposes upon boiling and should be stored at 28C in tightly closed containers.


Pharmaceutical Applications and Compliance

As a potent antihistamine, Olopatadine Hydrochloride is utilized in the treatment of allergic conjunctivitis and associated symptoms. It meets ICH Q3C guidelines for residual solvents and strict limitations for related substances and heavy metals, ensuring its suitability for pharmaceutical formulations. The product is widely supplied, distributed, and manufactured across India.


Safe Storage and Handling Guidelines

To maintain its quality and efficacy, Olopatadine Hydrochloride should be stored in a tightly closed container between 28C, protected from light and moisture. Adhering to these storage recommendations helps ensure a shelf life of up to three years, preserving its optimal pharmacological activity.